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  Indian J Med Microbiol
 

Figure 6: Lung metastasis assay: BALB/c mice inoculated with 4T1 tumour cells. (a) 1x105 4T1 cells were pre-treated for 24 hours with vehicle or 100 nM Dasatinib, then injected via tail vein into BALB/c mice. (b) Mice were injected via tail vein with 5x104 4T1 cells, then treated for five days with vehicle or 5, 15, or 30 mg/kg Dasatinib. (c) Representative photographs of lungs are shown. Arrows indicate representative metastasis. Median values are shown. Wilcoxon matched pairs test was used to analyse data in GraphPad Prism 6.0. *P<0.05, **P<0.01

Figure 6: Lung metastasis assay: BALB/c mice inoculated with 4T1 tumour cells. (a) 1x105 4T1 cells were pre-treated for 24 hours with vehicle or 100 nM Dasatinib, then injected via tail vein into BALB/c mice. (b) Mice were injected via tail vein with 5x104 4T1 cells, then treated for five days with vehicle or 5, 15, or 30 mg/kg Dasatinib. (c) Representative photographs of lungs are shown. Arrows indicate representative metastasis. Median values are shown. Wilcoxon matched pairs test was used to analyse data in GraphPad Prism 6.0. *<i>P</i><0.05, **<i>P</i><0.01