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Figure 2: Overexpression of Snail alters the fluctuations of the metabolites on the central metabolic pathways in A549 cells. A549-Snail cells were grown in the absence (black bars) or presence (white bars) of 2 mg/ml Dox for 2 days. The levels of the metabolites of glycolysis (blue shaded), tricarboxylic acid cycle (green shaded), and nucleotide synthesis (gray shaded) were measured using liquid chromatography-coupled tandem mass spectrometry/mass spectrometry analysis. *P < 0.05 (t-test) |
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