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  Indian J Med Microbiol
 

Figure 6: Knockdown of glycine decarboxylase induces a shift of cellular function from proliferation to migration in A549 cells. A549 cells were transfected with either the scrambled (siControl) or glycine decarboxylase-specific siRNA oligos for 2 days. (a) The levels of glycine decarboxylase and GAPDH proteins were measured using Western blotting. (b) The number of migratory cells was measured using Boyden chamber assay. **P < 0.01 (t-test). (c) A549 cells were transfected with either the siControl or siGLDC oligos, and the growth kinetics of the transfected cells were measured using cell counting within the indicated time frame. **P < 0.01 (t-test)

Figure 6: Knockdown of glycine decarboxylase induces a shift of cellular function from proliferation to migration in A549 cells. A549 cells were transfected with either the scrambled (siControl) or glycine decarboxylase-specific siRNA oligos for 2 days. (a) The levels of glycine decarboxylase and GAPDH proteins were measured using Western blotting. (b) The number of migratory cells was measured using Boyden chamber assay. **<i>P</i> < 0.01 (<i>t</i>-test). (c) A549 cells were transfected with either the siControl or siGLDC oligos, and the growth kinetics of the transfected cells were measured using cell counting within the indicated time frame. **<i>P</i> < 0.01 (<i>t</i>-test)