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  Indian J Med Microbiol
 

Figure 3: The metabolic changes in tumor microenvironment and the effect of that on the differentiation function of immune cells and cancer cells. The metabolic properties of a tumor are influenced by both intrinsic and extrinsic factors. Cell intrinsic factors are the metabolic programs active in each cell type. Extrinsic variables are the nutrient availability, waste and pH gradients, oxygen (O2) tension, and oxidative pressures

Figure 3: The metabolic changes in tumor microenvironment and the effect of that on the differentiation function of immune cells and cancer cells. The metabolic properties of a tumor are influenced by both intrinsic and extrinsic factors. Cell intrinsic factors are the metabolic programs active in each cell type. Extrinsic variables are the nutrient availability, waste and pH gradients, oxygen (O<sub>2</sub>) tension, and oxidative pressures